Peri-implant femoral fractures: Challenges, outcomes, and proposal of a treatment algorithm / 中华创伤杂志(英文版)

PURPOSE@#Non-prosthetic peri-implant fractures are challenging injuries. Multiple factors must be carefully evaluated for an adequate therapeutic strategy, such as the state of bone healing, the type of implant, the time and performed personnel of previous surgery, and the stability of fixation. The aim of this study is to propose a rationale for the treatment.@*METHODS@#The peri-implant femoral fractures (PIFFs) system, a therapeutic algorithm was developed for the management of all patients presenting a subtype A PIFF, based on the type of the original implant (extra- vs. intra-medullary), implant length and fracture location. The adequacy and reliability of the proposed algorithm and the fracture healing process were assessed at the last clinical follow-up using the Parker mobility score and radiological assessment, respectively. In addition, all complications were noticed. Continuous variables were expressed as mean and standard deviation, or median and range according to their distribution. Categorical variables were expressed as frequency and percentages.@*RESULTS@#This is a retrospective case series of 33 PIFFs, and the mean post-operative Parker mobility score was (5.60 ± 2.54) points. Five patients (15.1%) achieved complete mobility without aids (9 points) and 1 (3.0%) patient was not able to walk. Two other patients (6.1%) were non-ambulatory prior to PPIF. The mean follow-up was (21.51 ± 9.12) months (range 6 - 48 months). There were 7 (21.2%) complications equally distributed between patients managed either with nailing or plating. There were no cases of nonunion or mechanical failure of the original implant.@*CONCLUSION@#The proposed treatment algorithm shows adequate, reliable and straightforward to assist the orthopaedic trauma surgeon on the difficult decision-making process regarding the management of PIFF occurring in previously healed fractures. In addition, it may become a useful tool to optimize the use of the classification, thus potentially improving the outcomes and minimizing complications.

Manejo clínico de la hipertensión arterial pulmonar. Relevancia del ventrículo derecho / Relevance of right ventricle in the clinical management of pulmonary arterial hypertension

Resumen La hipertensión arterial pulmonar (HAP) requiere procesos estructurados de diagnóstico y estratificación de riesgo, siendo la función del ventrículo derecho (VD) un marcador pronóstico central. Los principales objetivos terapéuticos en la HAP son mejorar y/o intentar revertir la disfunción del VD y mantener condición de bajo riesgo. Actualmente existen múltiples fármacos con diferentes mecanismos de acción cuya combinación en doble o triple terapia ha mostrado mejores resultados que la monoterapia. Evidencia actual demuestra la importancia de incorporar tempranamente prostanoides parenterales al esquema, mejorando la funcionalidad del VD y la supervivencia. En esta revisión se refleja el papel de la función del VD en el diagnós tico, pronóstico y seguimiento de la HAP. Se recomienda la evaluación sistemática y estandarizada del VD, así como el inicio temprano de tratamiento combinado en riesgo intermedio-alto para obtener las metas de alcanzar y mantener un riesgo bajo y/o evitar la progresión de la HAP.

Abstract Pulmonary arterial hypertension (PAH) requires structured processes of diagnosis and risk stratifica tion, being the function of the right ventricle (RV) a hallmark prognosis determinant. The main therapeutic goals in PAH are to improve and try to revert RV dysfunction and maintaining a low risk. Currently, there are multiple treatments with different mechanisms of action, the combination of which in double or triple therapy has shown improved results compared to monotherapy. Recent clinical evidence shows the importance of early incorpora tion of parenteral prostanoids to the scheme, improving RV function and survival. In this review, we discuss the role of the RV function in the diagnosis, prognosis, and follow-up of PAH. We recommend the systematic and standardised evaluation of the RV as well as the early initiation of combined treatment in cases of intermediate-high risk to try to reach and keep the patient with PAH at a low risk and / or avoid the progression of PAH.

A clinicoradiological classification and a treatment algorithm for traumatic triceps tendon avulsion in adults / 中华创伤杂志(英文版)

PURPOSE@#Triceps tendon avulsion (TTA) is an uncommon injury, and there are no classifications or treatment guidelines available. This study aims to describe a clinicoradiological classification and treatment algorithm for traumatic TTA in adults. The functional outcome of surgical repair has been evaluated too.@*METHODS@#A retrospective analysis of adult patients with traumatic TTA treated in our institution between January 2012 and December 2017 was done. We only included complete TTA injuries. Children below 15 years, with open injuries, associated fractures, or partial TTA were excluded. The data were obtained from hospital records. The intraoperative findings were correlated with the clinicoradiological presentation for classifying TTA. The functional outcome was analyzed using the Mayo Elbow Performance index and Hospital for Special Surgery elbow score. ANOVA test was used to assess the statistical significance.@*RESULTS@#There were 15 patients included, 11 males and 4 females. The mean age was (31.5 ± 9.15) years, and the mean follow-up was (22.4 ± 8.4) months. Fall on outstretched hand was the mode of injury. In 6 patients, diagnosis was missed on the initial visit. TTA were classified as Type I: palpable soft-tissue defect without bony mass; Type II: palpable soft-tissue defect with a wafer-thin/comminuted bony fragment on X-ray; Type III: palpable soft-tissue defect with a bony mass and a large bony fragment on X-ray without extension to the articular surface; and Type IV: an olecranon fracture with less than 25% of the articular surface. An algorithm for treatment was recommended, i.e. transosseous suture repair/suture anchor for Type I, transosseous suture repair for Type II, and tension band wiring or steel wire sutures for Types III and IV. All the patients achieved good to excellent outcome: the mean Mayo Elbow Performance index was 100 and Hospital for Special Surgery score was 98.26 ± 2.60 on final follow-up.@*CONCLUSION@#Our clinicoradiological classification and treatment algorithm for TTAs is simple. Surgical treatment results in excellent functions of the elbow. Since it is a single-center study involving a very small number of cases, a multicenter study with a larger number of patients is required for external validation of our classification and treatment recommendations.

Posterior shoulder fracture-dislocation: A systematic review of the literature and current aspects of management / 中华创伤杂志(英文版)

PURPOSE@#Posterior fracture-dislocation of shoulder is an infrequent traumatic event; however, most orthopaedic surgeons may face the challenge of treating it. The aim of this study is to review and summarise systematically the current principles of the management of this complex injury, and create a treatment algorithm.@*METHODS@#Both PubMed and Scopus Databases were systematically searched for the terms "posterior shoulder fracture-dislocation" or "posterior glenohumeral fracture-dislocation" or "posterior glenoid fracture-dislocation" for articles written in English and published in the last decade.@*RESULTS@#A total of 900 articles were identified, of which 13 were retained for analysis. A total of 153 patients (161 shoulders) were identified. These patients were treated either with open reduction and internal fixation, modified McLaughlin procedure, allograft/autograft humeral head reconstruction or shoulder arthroplasty. The mean age was 40.15 years. The mean postoperative Constant score in cases treated by open reduction and internal fixation was 86.45, whereas by bone graft was 84.18. Further, the mean postoperative Constant score was between 79.6 and 67.1 in those that were managed by modified McLaughlin and arthroplasty procedure, respectively.@*CONCLUSION@#The management of posterior shoulder fracture-dislocation may be challenging, and the best surgical option depends on many variables such as the chronicity of the injury, the presence of a fracture at the level of the surgical neck or tuberosities and the extend of the Hill-Sachs lesion if any. A treatment algorithm is proposed, based on the current literature in an effort to create a consensus for these injuries. For the acute shoulder fracture-dislocations, an open reduction should be performed. For the chronic fracture/dislocations in the elderly low-demand patients, conservative treatment should be performed. For the rest of the patients, depending on the severity of the Hill-Sachs lesion different surgical options are available such as the McLaughlin technique, the use of an allograft, osteotomy or arthroplasty.

New Injury Mechanism and Treatment Algorithm of Posterior Elbow Dislocation

Although the concept of a single elbow dislocation mechanism, in which all dislocations start from the lateral side of the elbow joint and progress to the medial side, has never been able to explain the various conflicting experimental and clinical observations thus far, new studies and proposals for a valid mechanism have not been reported. The new proposal for posteromedial and posterolateral dislocation of the elbow joint according to the authors' study and the new treatment algorithm based on this new study can explain the various clinical and experimental results that have been difficult to explain, and provide a reasonable approach to the treatment of elbow dislocations.

Resección Mínimamente Invasiva de Quistes Sinoviales Espinales. Nota Técnica / Minimally Invasive Resection of Spinal Synovial Cysts. Technical note

Objetivo: Presentar el algoritmo de tratamiento, técnica quirúrgica y resultados de una serie de pacientes con quistes sinoviales espinales resecados con técnica mínimamente invasiva (MIS). Introducción: Los quistes sinoviales espinales se originan a partir de la dilatación y potencial ruptura de la vaina sinovial de una articulación facetaria. La resección quirúrgica es considerada el tratamiento de elección en pacientes sintomáticos. La utilización de técnicas MIS podrían disminuir la disrupción de la faceta articular comprometida reduciendo el riesgo de inestabilidad postoperatoria. Material y métodos: Se evaluaron retrospectivamente 21 pacientes con quistes sinoviales espinales operados mediante abordaje y descompresión MIS, se analizaron los signos, síntomas, tiempo quirúrgico, estadía hospitalaria, evolución y complicaciones. Se utilizó la escala visual analógica (EVA), para evaluar el dolor y la escala de Weiner y los criterios de Macnab modificados para medir la satisfacción posoperatoria del paciente. Resultados: Se trataron quirúrgicamente 21 pacientes (13 mujeres, 8 hombres), el 76,2% (n=16) de los pacientes de la serie no requirió artrodesis, el 23,8% (n=5) restante fue fusionado. Realizamos 13 (61,9%) hemilaminectomías contralaterales, 7 hemilaminectomías ipsilaterales (33,3%) y una laminectomía en el QS S1-S2 con técnica MIS. El seguimiento promedio fue de 26 meses, el tiempo de cirugía fue de 150,33 ± 63,31 min., con una estadía hospitalaria de 2,5 ± 1,78 días. La EVA disminuyó de 8,3 preoperatoria a 2,3 postoperatoria. Siguiendo la escala de Macnab; 16 pacientes refirieron resultados excelentes, 4 buenos y 1 regular, el 95,2% de los pacientes percibió que el procedimiento tuvo mucho/bastante éxito según la escala de Weiner. Conclusión: El abordaje mínimamente invasivo es un procedimiento seguro y eficaz para la resección completa de quistes sinoviales espinales. Proporciona resultados clínico-funcionales excelentes preservando músculos, ligamentos y facetas articulares.

Introduction: Spinal synovial cysts originate from the dilation and potential rupture of a facet joint's synovial sheath. Surgical resection is considered the treatment of choice in symptomatic patients; however, the use of minimally-invasive surgery (MIS) techniques could reduce any disruption of the facet joint involved, reducing the risk of postoperative instability. Objective: To present the treatment algorithm, surgical technique and results in a series of patients with spinal synovial cysts treated by MIS. Methods and Materials: We retrospectively evaluated 21 patients with spinal synovial cysts who underwent therapeutic MIS with decompression. Signs, symptoms, surgical time, hospital stay, course and complications were evaluated. A visual analog scale (VAS) was used to rate pain, while the Weiner scale and modified Macnab criteria were employed to measure patients' postoperative satisfaction. Results: Twenty-one patients were surgically treated with MIS, among whom 76.2% (n = 16) required no arthrodesis; the remaining 23.8% (n = 5) were fused. We performed 13 (61.9%) contralateral hemilaminectomies, seven ipsilateral hemilaminectomies (33.3%), and one laminectomy at S1-S2. The average follow-up was 26 months, surgical time 150.33 ± 63.31 minutes, and mean hospital stay 2.5 ± 1.8 days. The VAS pain rating decreased from 8.3 preoperatively to 2.3 postoperatively. Sixteen patients reported excellent results, four good and one fair. On the Macnab scale, all but one patient (1/21, 4.8%) perceived that the procedure had been very/quite successful. Conclusions: Minimally-invasive surgery is a safe and effective approach for the complete resection of spinal synovial cysts. It provides excellent clinical and functional results, by preserving muscles, ligaments and facet joints.

Systematic approach to managing vernal keratoconjunctivitis in clinical practice: Severity grading system and a treatment algorithm.

Vernal keratoconjunctivitis is an ocular allergy that is common in the pediatric age group. It is often chronic, severe, and nonresponsive to the available treatment options. Management of these children is difficult and often a dilemma for the practitioner. There is a need to simplify and standardize its management. To achieve this goal, we require a grading system to judge the severity of inflammation and an algorithm to select the appropriate medications. This article provides a simple and practically useful grading system and a stepladder algorithm for systematic treatment of these patients. Use of appropriate treatment modalities can reduce treatment and disease‑related complications.

Diagnosis and Treatment for Deep Nontuberculous Mycobacteria Infection of the Hand and Wrist

PURPOSE: The purpose of this study was to present a systematic treatment method for nontuberculous mycobacteria (NTM) infection of the hand and wrist to gain better clinical outcomes. METHODS: 10 patients of deep NTM infection of the hand and wrist were reviewed. Extensive debridement was performed in all cases. When biopsy result suggested mycobacterial infection such as granulomatous inflammation, empirical tuberculosis medication was started. After culture confirmed NTM growth, the species was identified and in vitro sensitivity test was performed. Then medication was switched according to the results. Functional outcomes of the hand and wrist were measured by total active motion of the fingers and by range of motion of the wrist respectively. RESULTS: Diagnosis was tenosynovitis in seven patients, infective arthritis and osteomyelitis combined with tenosynovitis of the wrist in three patients. Two patients had recurred skin ulcer during follow-up period and undergone second debridement. After second operation, no patient had a persistent discharging sinus and all patient were completely healed during follow-up period. Functional outcome of the eight patients who had NTM infection of their hand was excellent in two, good in four, fair in one, poor in one. Mean range of motion of the two patients who had osteomyelitis of their wrist was dorsiflexion 20degrees, volar flexion 15degrees, radial deviation 0degrees, ulnar deviation 15degrees. CONCLUSION: Our standardized treatment protocol can be helpful for treatment of deep NTM infection of the hand and wrist.

Treatment Algorithm of Complications after Filler Injection: Based on Wound Healing Process

Soft tissue filler injection has been a very common procedure worldwide since filler injection was first introduced for soft tissue augmentation. Currently, filler is used in various medical fields with satisfactory results, but the number of complications is increasing due to the increased use of filler. The complications after filler injection can occur at any time after the procedure, early and delayed, and they range from minor to severe. In this review, based on our experience and previously published other articles, we suggest a treatment algorithm to help wound healing and tissue regeneration and generate good aesthetic results with early treatment in response to the side effects of filler. Familiarity with the treatment of these rare complications is essential for achieving the best possible outcome.

Korean Treatment Algorithm for Obsessive-Compulsive Disorder 2007(III): A Preliminary Study for Application of Cognitive-Behavioral Therapy / 대한정신약물학회지

OBJECTIVE: The Korean College of Neuropsychopharmacology developed a Korean treatment algorithm for obsessive-compulsive disorder (OCD) to aid clinical decisions. The goal of this preliminary study was to encourage clinical practitioners to treat patients using cognitive-behavioral therapy. METHODS: We sent a questionnaire to 34 leading experts on OCD to investigate their opinions about treating patients with OCD using cognitive-behavioral therapy. RESULTS: Of the 34 experts, 12 responded to the survey. The responses indicated that most patients with obsessive-compulsive disorder should be offered cognitive-behavioral therapy, incorporating intensive and sufficient cognitive therapy with response prevention. CONCLUSION: These results may provide information about the application of cognitive-behavioral therapy to treat obsessive-compulsive disorder.

Korean Treatment Algorithm for Obsessive-Compulsive Disorder 2007(III): A Preliminary Study for Application of Cognitive-Behavioral Therapy / 대한정신약물학회지

OBJECTIVE: The Korean College of Neuropsychopharmacology developed a Korean treatment algorithm for obsessive-compulsive disorder (OCD) to aid clinical decisions. The goal of this preliminary study was to encourage clinical practitioners to treat patients using cognitive-behavioral therapy. METHODS: We sent a questionnaire to 34 leading experts on OCD to investigate their opinions about treating patients with OCD using cognitive-behavioral therapy. RESULTS: Of the 34 experts, 12 responded to the survey. The responses indicated that most patients with obsessive-compulsive disorder should be offered cognitive-behavioral therapy, incorporating intensive and sufficient cognitive therapy with response prevention. CONCLUSION: These results may provide information about the application of cognitive-behavioral therapy to treat obsessive-compulsive disorder.

Korean Treatment Algorithm for Obsessive-Compulsive Disorder 2007(IV): Comorbid Conditions / 대한정신약물학회지

OBJECTIVES: Patients with obsessive-compulsive disorder (OCD) frequently exhibit complex clinical features, including comorbidity with other psychiatric disorders, which challenge diagnostic and therapeutic practice. This study presents a number of Korean experts' ratings of the appropriateness of treatments for patients with comorbid OCD and other psychiatric disorders. METHODS: The Korean Treatment Algorithm Project for Obsessive-Compulsive Disorder (KTAP-OCD 2007) developed a questionnaire that included questions about seven psychiatric comorbid conditions: major depressive disorder, bipolar disorder, panic or social anxiety disorder, schizophrenia, attention deficit hyperactive disorder (ADHD), oppositional/conduct/antisocial disorder, and Tourette disorder. Answers from 24 respondents were analyzed to assess first-line and second-line treatments for each comorbid condition. RESULTS: Experts selected cognitive behavior therapy (CBT) in conjunction with medication as the treatment for comorbidity with major depressive disorder, anxiety disorders, ADHD, or Tourette disorder. They selected a selective serotonin reuptake inhibitor (SSRI) combined with atypical antipsychotics as the treatment of choice for patients with comorbid OCD and schizophrenia. When patients had comorbid OCD and bipolar disorder, experts preferred adjunctive serotonin reuptake inhibitors to CBT. In all cases, experts were less likely to select clomipramine for second-line treatment. CONCLUSION: The findings from the KTAP-OCD 2007 survey on psychiatric comorbid conditions were generally consistent with foreign guidelines. However, more guidelines might be required for comorbidity with bipolar disorder and the use of clomipramine.

Korean Treatment Algorithm for Obsessive-Compulsive Disorder 2007(IV): Comorbid Conditions / 대한정신약물학회지

OBJECTIVES: Patients with obsessive-compulsive disorder (OCD) frequently exhibit complex clinical features, including comorbidity with other psychiatric disorders, which challenge diagnostic and therapeutic practice. This study presents a number of Korean experts' ratings of the appropriateness of treatments for patients with comorbid OCD and other psychiatric disorders. METHODS: The Korean Treatment Algorithm Project for Obsessive-Compulsive Disorder (KTAP-OCD 2007) developed a questionnaire that included questions about seven psychiatric comorbid conditions: major depressive disorder, bipolar disorder, panic or social anxiety disorder, schizophrenia, attention deficit hyperactive disorder (ADHD), oppositional/conduct/antisocial disorder, and Tourette disorder. Answers from 24 respondents were analyzed to assess first-line and second-line treatments for each comorbid condition. RESULTS: Experts selected cognitive behavior therapy (CBT) in conjunction with medication as the treatment for comorbidity with major depressive disorder, anxiety disorders, ADHD, or Tourette disorder. They selected a selective serotonin reuptake inhibitor (SSRI) combined with atypical antipsychotics as the treatment of choice for patients with comorbid OCD and schizophrenia. When patients had comorbid OCD and bipolar disorder, experts preferred adjunctive serotonin reuptake inhibitors to CBT. In all cases, experts were less likely to select clomipramine for second-line treatment. CONCLUSION: The findings from the KTAP-OCD 2007 survey on psychiatric comorbid conditions were generally consistent with foreign guidelines. However, more guidelines might be required for comorbidity with bipolar disorder and the use of clomipramine.